Naloxonum [Inn-Latin]
Brand names,
Naloxonum [Inn-Latin]
Analogs
Naloxonum [Inn-Latin]
Brand Names Mixture
Naloxonum [Inn-Latin]
Chemical_Formula
C19H21NO4
Naloxonum [Inn-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/naloxone.htm
Naloxonum [Inn-Latin]
fda sheet
Naloxonum [Inn-Latin]
msds (material safety sheet)
Naloxonum [Inn-Latin]
Synthesis Reference
No information avaliable
Naloxonum [Inn-Latin]
Molecular Weight
327.374 g/mol
Naloxonum [Inn-Latin]
Melting Point
200 - 205 oC
Naloxonum [Inn-Latin]
H2O Solubility
Soluble
Naloxonum [Inn-Latin]
State
Solid
Naloxonum [Inn-Latin]
LogP
1.464
Naloxonum [Inn-Latin]
Dosage Forms
Liquid
Naloxonum [Inn-Latin]
Indication
For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.
Naloxonum [Inn-Latin]
Pharmacology
Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
Naloxonum [Inn-Latin]
Absorption
Well absorbed following intramuscular injection.
Naloxonum [Inn-Latin]
side effects and Toxicity
No information avaliable
Naloxonum [Inn-Latin]
Patient Information
No information avaliable
Naloxonum [Inn-Latin]
Organisms Affected
Humans and other mammals